Amazon API Gateway, a service for creating and managing APIs, is an entry point and gatekeeper for many types of applications including web applications, containerized and serverless workloads, and mobile backends. To make the most of this service, you need to know exactly which features to use, how to use them, and under which conditions. In this whitepaper, we explore seven reference architectural patterns that use API Gateway and their integration with Amazon CloudWatch. We also provide sample code that can be used as a reference for live projects. Read this whitepaper to understand best practices along with our recommendations for creating reliable and cost-effective solutions using Amazon API Gateway.